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[jobeard]

If you have this condition, perform a clean install - - nothing else seems to work.

• A small number of users are unable to install Microsoft Office due to a persistent .NET Framework 4 corruption issue in Windows 7. It is unclear exactly how many users are affected -- it's clearly not the majority, but it's also clear that it's more than just 1 or 2 (remember also there's millions of MSO users).
  
• Microsoft has known about this problem for over a year and has thus far been unable to fix it.
  
• The only solution at this point is a clean install of Windows. In some cases repair installations and other tricks will not solve the underlying problem.
  
• The problem makes users unable to install Internet Explorer 9 and Microsoft Office.
  
• The problem affects users with a variety of hardware configurations (HP, Dell, Apple, etc.) and a variety of operating system versions (from Windows 7 Home Premium 32-bit to my own Windows 7 Professional 64-bit).

(kb308096 from 2007 does not address win/7)

Posted locally in New and Links

Original source of information is here

PS: A utility to test the .Net Framework install and configuration can be downloaded from here